Towards open science
Michal H. Kolář
UCT Prague
November 25, 2020
for Masaryk University, Brno, CZE
Acknowledgement
→ Běstvina Summer School, IOCB Prague, MPI BPC Göttingen
→ slides written in HTML/CSS with the Reveal.js library
→ slides available https://mhkoscience.github.io/muni-openscience
→ icons: Adrien Coquet, dewadesign, Grégory Montigny, HAMEL KHALED, Massupa Kaewgahya, Musmellow, Rflor from the Noun Project
Walther Hermann Nernst
about 10 years before he bought his first car.
- German physical chemist
- Nobel prize winner (1920)
- inventor of a lamp with ceramic filament
Scientists need freedom and money to explore and discover.
Citizen Science
Search for Extraterrestrial Intelligence
Using idle desktop computers to analyze data from Arecibo Observatory.
Folding@home (Stanford, US)
Rosetta@home (Uni Washington, US)
Proteins
"How come that so simple polymer ends up in one highly stable 3D conformation?"
Levinthal's paradox
Foldit
Mason-Pfizer monkey virus (M-PMV) protease
Cooperative effort of several research groups with Foldit players.
Involved IOCB Prague.
Shoot for the moon. Even if you miss, you'll land among the stars.
Norman Vincent Peale
We break away from the traditional paradigm in drug discovery - open data without intellectual property constrains.
Are there any common principles?
Transparency
Accessibility of data and tools
Public engagement
Intellectual independence
Many formal projects
FAIR guiding principles: Wilkinson et al. 2016
- findable
- accessible
- interoperable
- reuseable
FORSTER: e-learning portal
- EU-funded open science project
- accessibility
- interoperability
- reuseability
Utrecht University (NL) Open Science Program
Otevřená věda by Czech academy of sciences
What can you do in practice?
Share your work
Share your results
- use unique identifiers
- publish in OA journals
- use preprint servers
- consider open review both as author and reviewers
Communicate with public
- use social networks
- use virtual social networks
- put your work in wider context
Opening the science puts higher demands on the critical assessment of its content.
web: mhko.science/p/contact
twitter: @mhkoscience
A Python bug of a closed-source code for NMR analysis.
OS-dependent sorting of files lead to wrong Boltzmann weights in their algorithm.
